BFACE3-BDAE0 Abstract It is now generally accepted that vitamin D deficiency is a worldwide health problem that affects not only musculoskeletal health but also a wide range of acute and chronic diseases. However, there remains cynicism about the lack of randomized controlled trials to support the association studies regarding the nonskeletal health benefits of vitamin D. This review was obtained by searching English-language studies in PubMed, MEDLINE, and the Cochrane Central Register of Controlled Trials and focuses on recent challenges regarding the definition of vitamin D deficiency and how to achieve optimal serum hydroxyvitamin D concentrations from dietary sources, supplements, and sun exposure. The effect of vitamin D on fetal programming epigenetics and gene regulation could potentially explain why vitamin D has been reported to have such wide-ranging health benefits throughout life.
Clearly, the case is not closed. Clinical data demonstrate that ascorbic acid potentiates chemotherapy effects.
The majority of clinical evidence indicates the usefulness of antioxidants, like vitamin C, concurrently with most types of chemotherapy.
|Health News Report: Health Benefits of Vitamin C||Health Benefits of Vitamin C Vitamin C may help people who suffer from respiratory symptoms after exercise Physical activity increases oxidative stress, and therefore, as an antioxidant vitamin C might have particularly evident effects on people who are participating in vigorous exercise.|
|Positive Health Online | Article - Vitamin C and Cancer - Storm of Controversy||However, the effectiveness of any dose over the recommended daily allowance has generated debate and controversy in medical, research, and alternative medicine fields.|
|Associated Data||Widely recognized as a powerful antioxidant, vitamin C has been the subject of nearly 5, scientific studies, published in PubMed, examining its role in cancer prevention or therapy, although for the most part, the medical community continues to rely almost entirely on invasive and dangerous treatments, such as radiation, surgery and chemotherapy.|
|Vitamin D for Health: A Global Perspective||Learn More Hazel Hazel had been given a virtual death sentence by her cancer doctor, telling her that although there was an 86 percent recovery from her type of breast cancer, she was unfortunately in the smaller category.|
In the September issue of The Journal of Oncology an article appeared in which the authors discuss possible theoretical negative interactions of cancer chemotherapy drugs and concurrent use of antioxidants.
Splenic and thymic weights of the vitamin-treated animals were higher than those receiving cytotoxic treatment alone, suggesting an immune-stimulating action of the vitamins. As well as being safe to use concurrently with chemotherapeutic agents, vitamin C has also been shown safe to be used concurrently with radiation.
Furthermore, he states, "There can be no logical reason today why most of the research funds should go only toward the examination of more chemotherapy and more ways of giving radiation.
There must be a major expansion into the use of orthomolecular therapy to sort out the variables and to determine how to improve the therapeutic outcome of treatment.
The redox potential of an element is an expression of potential energy and potential ability to do work the energy potential of a molecule is related to the minus number of electrons.
The redox potential is directly linked to the effectiveness of the immune system and inflammatory resolution. Therefore, effective cancer modulation can be thought of as a product of the redox potential, or, in other terms, antioxidant capacity.
The role of antioxidants as cancer modulative, palliative and a treatment agent is a topic of hot emotional and scientific controversy.
What is not commonly appreciated is that tumours exhibit sensitivity to free radical damage and to high concentrations of antioxidants.
Numerous studies have shown that tumour cells are lacking in catalase, glutathione peroxidase, manganese SOD superoxide dismutase and copper-zinc SOD. This indicates that tumour cells lack free radical protective mechanisms.
Further evidence for this lies in the fact that many of the chemotherapeutic agents utilized today act via the generation of highly reactive free radicals, which cause damage to malignant cells and normal cells too, unfortunately.
The million-dollar question is: If malignant cells lack antioxidant protection mechanisms, how then can antioxidants be employed against tumour cells? The answer, again, seems to lie in the fact that tumour cells lack antioxidant homeostatic mechanisms and can neither protect themselves from the damages of free radicals nor adapt to high doses of antioxidants and incorporate them into their defence mechanisms.
Therefore, high-dose antioxidant therapy has two beneficial modes of action. One is through direct tumourcidal effects and one is by protecting normal cells from the damage of the immune system generating free radicals. Ascorbic acid and ascorbic acid salts are preferentially toxic to tumour cells, which is thought to be related to intracellular generation of hydrogen peroxide.
This paradox is explained by the lack of antioxidative homeostatic mechanisms of malignant cells versus normal cells. The main mechanism thought to be responsible for this is the lack or relative deficiency of catalase in tumour cells.
Antioxidants act as electron carriers, coenzymes act as electrical circuits, and fats and antioxidants are the insulation. Irwin Stone demonstrated this brilliantly with his work in showing that the ratio of reduced to oxidized ascorbate was highly correlated to morbidity, convalescence and mortality.
He found that when the ratio was equal to one, the patient would die. In other words, when the electric potential was zero, life ceased.
The electrical systems for generating energy, blocking extra free radical production, creating immunity and protecting against cancer are the same electrical system. That electrical system is redox. Why then is ascorbic acid so important? Because it is considered the main redox stabilizer, stabilizing oxidation-reduction reactions in the body.
His theory explained how evolution was shaped by the loss of the chemical machinery required to make essential nutrients.The Controversy Surrounding the Health Benefits of Vitamin C Regading Prevention of Cancer.
For bone health and chronic disease prevention, many people are likely to need more vitamin D than even these new government guidelines recommend. damage, and this may explain these findings. Still, more research is needed before we can be confident of these benefits. Vitamin D and Cancer. In the meantime, based on the evidence to date.
Based on the lack of conclusive evidence for a benefit of vitamin E supplementation in cancer and cardiovascular disease prevention in generally healthy adults and the potential for harm in certain subpopulations, the Linus Pauling Institute has revised its "Rx for Health" and no longer includes a recommendation for supplementation with IU.
The Myriad Benefits of Vitamin C – How Vitamin C can be a key player in your Health. They includes cancer, cardiovascular disease, osteoporosis, chronic fatigue, diabetes, and viral conditions like hepatitis, herpes and cytomegalovirus.
Recent research has found that Vitamin C kills TB. Death by doctoring Benefits of vitamin c. In terms of its benefits in cancer treatment and prevention, Phillip Day notes, “Dr. Linus Pauling, often known as the ‘Father of Vitamin C’ and twice awarded the Nobel Prize, declared that daily intakes of up to 10g of the .
Vitamin D Cancer Prevention and Other New Uses March Benefits for Breast Health. Technically, vitamin D is not a true vitamin. Since sun exposure can stimulate its synthesis in the body, it is not necessarily required in the diet, except in certain circumstances. Furthermore, its structure and mechanism of action more closely.